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To provide world class, quality care while delivering on unparalleled patient experience.

Welcome to the KSK Cancer Center of Irvine (CCOI) a privately owned comprehensive medical center which offers top quality treatment and care from our finest medical faculty; handpicked for their expertise, years of experience and quality of care. Our dedicated team of experts are deeply involved in innovative cancer treatments, revolutionary cancer research, and patient education. CCOI also works closely with many well-respected physicians in our community and across the country to ensure the best patient care.

CCOI offers the highest quality cutting edge Radiation Oncology treatments for various cancers. We specialize in external beam radiotherapy, brachytherapy, administration of radioactive unsealed sources, and various other cancer treatments.  We are highlighted by our expertise internationally in both prostate and breast cancer treatment. CCOI also has an extensive background in treating many other areas such as lung, gastrointestinal, genitourinary, gynecological, skin, brain and palliative cases. Our cure rates remain among the best in the country.                     

KSK Cancer Center of Irvine is truly devoted to patients & their families!  


“I can recommend the Cancer Center of Irvine very highly.  My wife and I have been very impressed with my entire treatment.  Drs. Tokita and Yeh are outstanding and are always available for a consultation and to answer your questions.  The staff is very professional, efficient, well teamed, and knowledgeable.  They care about the patient and the patients comfort.  I could always get answers to any of my question.  I dreaded the long drive from my home to Irvine, every day for my treatment but, very soon, I felt it was definitely worth it to have such excellent treatment here.” – Jay

“We want to thank each and every person in this office for saving my husband’s life.  You are a wonderful credit to Dr. Tokita, the man responsible for helping so many.  We will be forever grateful for having this experience and will cherish being of the “family.”  Thank you again.  You will always be in our thought and prayers!!”  Love Judy

“I very much appreciate the outstanding medical treatment that I have been receiving at your facility.  You have a staff that is not only well trained but also extremely concerned with patient satisfaction.  On top of this, they are very courteous.” – Ken

“Your entire Team is absolutely amazing!  Up Beat, smiling, polite, caring, great sense of humor, courteous….so many consistent qualities making my visits most comfortable & pleasant.  Thank you!” - Michael

“…You took what is a somewhat scary journey and made it an exciting adventure…Thanks a million!” - Ron


Facts about Prostate Cancer Radiation Treatment and SpaceOAR

Treatment options: There are two very effective ways of treating and curing Prostate Cancer, Surgery and Radiation Therapy.

How Radiation Works: The two modalities for Radiation Therapy involve external beam therapy, where the radiation enters from the outside and is targeted to the area of interest, and brachytherapy which targets the area of interest from the inside by use of radioactive sources.

Side Effects:  As with any treatment, there are potential side effects. The two potentially serious side effects of radiation for prostate cancer is an injury or “burn” of the anterior rectum and the other is to the Urethra (urine drainage tube) that drains the urine through the prostate and penis.  Until recently, the most serious was the rectal injury or “burn”. In its most serious form, the injury leads to an ulceration of the lining of the rectum. When the stool with very high concentrations of bacteria passes, this leads to persistent infections. This may cause diarrhea, pain, bleeding and frequent uncontrolled bowel movements and fecal incontinence (soiled pants).


Research and Development: The Cancer Center of Irvine, with funding from the Medici Foundation, developed a technique to “protect” the rectum. Recently, the FDA approved this material called SpaceOAR which accomplishes this protection.


Spacer Material: To help avoid this injury, the space between the prostate and rectum is increased by injecting an absorbable gel. This can push the rectum away from the prostate by ½ to 1 inch, which is out of the high dose radiation area. For radiation, this is an enormous distance and dramatically enhances the safety for the rectum. The distance allows the Doctors to be more aggressive in treating the prostate and lead to higher cure rates.


Data: The Cancer Center of Irvine is the lead developer of the spacer material and we have dramatically decreased the rectal symptoms and injuries. We have treated over 820 patients with this technology with amazing results.


Historical Development

1998 - Dr. Tokita first saw a young actress have a gel injected into her face by a Plastic Surgeon. He felt this may have potential for protecting the rectum from radiation injury.
2002 - 7 different groups applied to the FDA for separate ways of protecting the rectum during prostate radiation.
2003 – Dr. Tokita solely received the only approval to pursue this research.
2008 - The trial concluded, 115 patients were successfully injected and treated.
2010 - Paper presented at a national meeting, and Dr. Tokita moved to a new more effective material called Ethylene Glycol (DuraSeal) used in Brain and Spinal cord surgery. He then developed the specifications for a company called Augmenix, who later developed SpaceOAR.
2015 - FDA gave official approval for the Augmenix (SpaceOAR material).



Over 35,000 patients receive radiation treatment for prostate cancer every year. Patients will greatly benefit from SpaceOAR, the rectal protection material, and will lead to probable increases in cure rates.

Greet-The-Day Spa Treatment For Our Female Patients

Every quarter year, we are fortunate to provide a spa day for 2 current or past patients that have had treatment at our center. The complimentary spa and lunch grants female patients the opportunity to socialize with other women that have been treated with various modalities of cancer care in the Orange County area. Please inquire within to sign up for our waiting list to attend the heartwarming event!

Radiation Therapy 101

What is Radiation Therapy?

Radiation Therapy is the medical use of ionizing radiation as part of cancer treatment to control cancer cells.


Varian 23 iX with OBI imaging

Uses of Radiation Therapy:

Radiation Therapy can be used for the primary course of treatment or in conjunction with surgery and/or chemotherapy. Depending on diagnosis and staging, radiation therapy is used for curative or palliative purposes.

Read more: Radiation Therapy 101